| Bioactivity | [Ala1,3,11,15]-Endothelin (53-63) (TFA) is an ETB agonist. [Ala1,3,11,15]-Endothelin (53-63) (TFA) has selectivity for ETB with IC50 values range from 0.33 nM to 0.61 nM. [Ala1,3,11,15]-Endothelin (53-63) (TFA) can be used for the research of vasoconstriction[1]. |
| Invitro | [Ala1,3,11,15]-Endothelin (53-63) (TFA) (0.1 μM) has selectivity for ETB with IC50 values of 0.61 nM, 0.61 nM, 0.33 nM, 2200 nM in Bronchus, Lung, Cerebellum and VSMC, respectively[1]. |
| Name | [Ala1,3,11,15]-Endothelin (53-63) (TFA) |
| Sequence | Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp |
| Shortening | ASASSLMDKEAVYFAHLDIIW |
| Formula | C111H164F3N25O34S |
| Molar Mass | 2481.70 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |